tumour necrosis factor การใช้

• The mechanism is thought to be mediated by tumour necrosis factor inhibition.
• Interleukin-1 and tumour necrosis factor are involved in cutaneous hyperalgesia.
• Tumour necrosis factor or Tumour necrosis factor-alpha?
• Tumour necrosis factor or Tumour necrosis factor-alpha?
• Infliximab works by binding tumour necrosis factor alpha.
• DOI has been shown to be an extremely potent inhibitor of tumour necrosis factor-alpha inflammation at picomolar concentrations in cell studies.
• It targets Tumour Necrosis Factor Related Apoptosis-inducing Ligand ( TRAIL ), whose receptors are found on the surface of many types of malignant cells.
• BTLA is a ligand for tumour necrosis factor ( receptor ) superfamily, member 14 ( TNFRSF14 ), also known as herpes virus entry mediator ( HVEM ).
• Taurolidine has been shown to block Interleukin 1 ( IL-1 ) and tumour necrosis factor ( TNF ) in human peripheral blood mononuclear cells ( PBMC ).
• Discovery of a feedback mechanism between the extracellular protease ADAM 8 and the inflammation signalling molecule tumour necrosis factor alpha ( TNFalpha ) ( with J鰎g-Walter Bartsch)
• Immunosuppressants such as interferon alpha and tumour necrosis factor antagonists may improve though not completely reverse symptoms of ocular Beh鏴t's, which may progress over time despite treatment.
• Feldmann's group demonstrated that diseased joints have far more pro-inflammatory cytokines than normal, and identified one of these, Tumour Necrosis Factor Alpha, abbreviated TNF? as the key.
• Finally, it was shown that, when endogenous NF-?B is induced by TNF? ( tumour necrosis factor ? ) treatment, HIF-1? levels also change in an NF-?B-dependent manner.
• T-lymphocytes start producing many cytokines ( interferon gamma, interleukin-2, tumour necrosis factor alpha, and macrophage colony-stimulating factor ) to activate macrophages and cytotoxic cells to inhibit their intracellular growth.
• The authors speculated on whether the mechanism could be the antiviral effect of the drug, the production of endogenous substances, such as endorphins, or interference with the production of interleukin-1 and tumour necrosis factor.
• Fas ligand ( FASLG or FasL ) and the tumour necrosis factor-related apoptosis-inducing ligand ( TNFSF10 or TRAIL ) might reflect an additional apoptotic mechanism induced by c-Fos, as observed in a human T-cell leukaemia cell line.
• In several clinical trials, cysteine supplementation improved skeletal muscle functions, decreased the body fat / lean body mass ratio, decreased plasma levels of the inflammatory cytokine tumour necrosis factor a ( TNF-a ), improved immune functions, and increased plasma albumin levels.
• 45 . Poturoglu S, Kaymakoglu S, Gurel Polat N, Ibrisim D, Ahishali E, Akyuz F, Badur S, Demir K, Mungan Z . A new agent for tumour necrosis factor-alpha inhibition : In vitro effects of dipyridamole in Crohn's disease.
• During sepsis, signalling by the inflammatory cytokines, interleukin-1 and tumour necrosis factor, mediate altered protein transcription in the systemic inflammatory response, resulting in decreased synthesis of the regulatory proteins antithrombin, protein C and protein S, with increased synthesis of prothrombotic proteins Factor VIII, von Willebrand factor, and fibrinogen.
• The expression of HA is known to down-regulate the recruitment of inflammatory cytokines tumour necrosis factor-alpha ( TNF-? ); since fetal wounds contain a reduced number of pro-inflammatory mediators than adult wounds it is thought that the higher levels of HA in the fetal skin aid in scar free healing.